Basic Research

Basic Research
08.05.2025 Nature. Mutated cells that divide rapidly are more prone to forming cancer Cancer starts when cells acquire genetic mutations that prompt them to proliferate out of control...

Los investigadores del CNIO Irene Herranz y Nabil Djouder. / Sladjana Zagorac. CNIO

Basic Research
06.05.2025 Nature Communications. CNIO researchers discover a molecular mechanism that initiates colon cancer Colorectal – colon or rectal – cancer is the third most diagnosed type of cancer...

Marcos Díaz Gay, head of the Digital Genomics Group at the CNIO (Spanish National Cancer Research Center), hired under the Building Generation AI program of Generation D /Laura M. Lombardía. CNIO

Basic Research
23.04.2025 Nature. Rise in colorectal cancer in young people may be due to bacterial infection in childhood Exposure during childhood to a bacterial toxin could be triggering an epidemic of colorectal cancer...

Tumour cell surrounded by platelets. / Mata Hergueta. CNIO

Basic Research
02.04.2025 Nature Communications. High-fat diet promotes breast cancer metastasis in animal models Obesity is associated with an increased risk of developing breast cancer, and a greater probability...

Researcher Marisol Soengas, head of the Melanoma Group at CNIO./ Pilar Gil. CNIO

Basic Research
28.03.2025 Nature Cancer. CNIO research reveals how melanoma and other tumours succeed in hiding and resisting immunotherapy Cutaneous melanoma, the most aggressive form of skin cancer, is characterised by its accumulation of...

Mouse macrophages visualized in confocal microscopy image. Nuclei are shown in blue and the actin network in orange. © Mónica Fernández Monreal, Bordeaux Imaging Centre

Basic Research
26.02.2025 Nature. The immune system extracts nutrients from the harmful bacteria it ingests, according to study with CNIO participation Macrophages are defensive cells that cleanse the body by destroying pathogens, such as bacteria and...

Basic Research
15.10.2024 Developmental Cell. New discovery on how cells build their internal skeleton Inside each cell, a network of tiny filaments, the microtubule cytoskeleton, helps maintain the...

Ana Ortega-Molina, primary author and current researcher at the Severo Ochoa Molecular Biology Centre, and Alejo Efeyan, senior author, from the CNIO Metabolism and Cell Signalling Group. Credit: /CNIO.

Basic Research
07.06.2024 Nature Aging. Aging speeds up and lifetime shortens in animals whose cells ‘believe’ to have too many nutrients, despite following a normal diet The reality of a population who is ageing at an accelerated rate makes it a priority to understand...

Tony Wyss Coray after his seminar at CNIO. Credit Laura M. Lombardía / CNIO.

Basic Research
14.05.2024 Blood could eventually become a tool against aging, Wyss-Coray says Research into different factors in the blood could contribute to better understanding and detecting...