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Structure of the LAT2/CD98hc protein Basic Research
29.11.2021
Spanish scientists determine the mode of action of essential proteins involved in cancer and Alzheimer´s disease The proteins that belong to the HAT family are essential for life as they transport amino acids...
Basic Research
17.08.2021
eLife. A master regulator gene for brain cancer with the worst prognosis Researchers at the CNIO and scientists from the School of Medicine of the University of Fribourg,...
Tumor pulmonar inducido por el KRAS4A. /CNIO Basic Research
19.07.2021
PNAS. CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in human cancer KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common...
Alejo Efeyan and Ana Ortega, CNIO Basic Research
13.07.2021
Cell Reports. CNIO researchers discover a new pathway to tackle follicular lymphoma For their own benefit and to grow beyond control, tumours manipulate cell signals to make it appear...
Estructura TELO2-TTI1-TTI2 complejo mTOR Basic Research
07.07.2021
Cell Reports. CNIO researchers help to decipher the structure of the large molecular machine that assembles and activates mTOR The principle that form follows function does not only apply to design and architecture. It also...
De izquierda a derecha: Ana Belén-Plata Gómez, Alejo Efeyan y Nerea Deleyto-Seldas. /CNIO Basic Research
16.06.2021
Nature Communications. A molecular switch that allows organisms to adapt to fasting conditions Getting energy and nutrients from the environment – that is, eating – is such an important...
PrimPol binds to damaged DNA Basic Research
15.06.2021
The EMBO Journal. A protein that facilitates DNA repair may potentiate chemotherapy Chemotherapy kills tumour cells by causing damage to them. One of the most effective ways of causing...
T7SS secretion system of 'M. tuberculosis' Basic Research
26.05.2021
Nature Reviews Microbiology. An international team reviews the latest advances in the understanding of the molecular mechanisms of tuberculosis Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, a bacterium that usually...
Mouse senescent epithelial cells, CNIO Basic Research
17.05.2021
Developmental Cell. A connection between senescence and stem cells caused by a breast cancer-initiating protein Early diagnosis and improvement of breast cancer treatments have reduced breast cancer mortality in...

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