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2) Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows indicate where replication begins, and the white arrows indicate the direction of copying of the molecule. The distance between the ends of the white arrows is about 100 thousandths of a millimeter (µM), or about 250,000 'letters' of DNA (bases). / Sara Rodríguez-Acebes. CNIO Basic Research
04.03.2024
The EMBO Journal. CNIO researchers discover a protein that prevents DNA triplication Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same...
Germinal center with normal structure on the left and aberrant due to lack of NGFR on the right. The maturing B lymphocytes are shown in green and the cells that generate the structure in red /Alberto Hernández. CNIO Basic Research
26.02.2024
Cell Reports. The molecule behind a potential new therapy for melanoma also plays a key role in autoimmune diseases Three years ago, in 2021, the Microenvironment and Metastasis Group at the Spanish National Cancer...
Basic Research
02.02.2024
Science. First atomic-scale ‘movie’ of microtubules under construction, a key process for cell division Cells in the human body are constantly dividing. With each division the genetic information...
Basic Research
21.07.2023
Researchers discover a molecule that helps pancreas cell mature and limits tumour formation The pancreas, located behind the stomach, manages the energy supply in our body. It does so by...
Basic Research
27.01.2023
One of the causes of aggressive liver cancer discovered: a ‘molecular staple’ that helps repair broken DNA Error-correcting mechanisms are very important for cells, because with all the cellular activity...
Basic Research
23.12.2022
Two Spanish researchers to lead the Proteomics and Confocal Microscopy Units at CNIO after a decade abroad Tumor cells have defective genes. Genes carry the instructions to make the biochemical building...
Basic Research
14.12.2022
Nature Communications. CNIO researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer Precision oncology aims at pointing out which drug is likely to work in every specific cancer...
Basic Research
05.12.2022
Molecular Cell. PrimPol, the enzyme that helps cells tolerate DNA damage, may contribute to the development of leukaemia Sometimes everything needs to be perfect, but sometimes it’s the opposite: you have to turn a...
Mechanism discovered that helps viruses like monkeypox to block and evade our cellular defence system Basic Research
24.11.2022
Nature Communications. Mechanism discovered that helps viruses like monkeypox to block and evade our cellular defence system A defence mechanism that human cells possess against viruses such as monkeypox, herpes simplex and...

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