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Basic Research

Basic Research
31.03.2020
Maria Blasco and Marisol Soengas of the CNIO receive 5 million euros in ‘ERC Advanced Grants’ from the European Union to tackle the immortality of cancer cells and metastasis Two of the major pending questions in the field of oncology are why tumour cells can divide...
mTOR activity in mice liver samples Basic Research
03.03.2020
Nature Communications. The CNIO finds that rapamycin has harmful effects when telomeres are short In the past few decades, it was discovered that the rate at which we age is strongly influenced by...
TOP II activity Basic Research
14.02.2020
Nature Communications. CNIO and Cabimer researchers show that DNA topological problems may cause lymphoma Researchers from the Spanish National Cancer Research Centre (CNIO), Madrid, and the Andalusian...
Mesothelioma CNIO Basic Research
07.01.2020
Cancer Research. Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice Exposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggressive...
Manuel Valiente, CNIO Basic Research
10.12.2019
Manuel Valiente receives the most prestigious European grant to study brain metastasis The brain, one of our most valuable and delicate organs, has developed tools to protect itself...
Mice mammary tissue FASN, CNIO Basic Research
04.11.2019
Nature Communications. A molecular strategy that helps prevent tumour formation in mice described The body’s process for manufacturing fatty acids is regulated by the enzyme FASN. In normal...
Normal vs hyper-long telomeres, CNIO Basic Research
17.10.2019
Nature Communications. CNIO researchers obtain the first mice born with hyper-long telomeres and show that it is possible to extend life without any genetic modification A chance finding ten years ago led to the creation by researchers of the Spanish National Cancer...
3D T7SS, CNIO Basic Research
09.10.2019
Nature. CNIO and the University of Würzburg solve the 3D structure of the ‘nanomachine’ that makes tuberculosis virulent An international team consisting of researchers from the Macromolecular Complexes in DNA Damage...
Normal mouse urothelial organoids Basic Research
04.10.2019
Nature Communications. A CNIO team uses organoid technology and single-cell RNA sequencing to advance in the study of bladder cancer Investigation of biological mechanisms in urothelial tissue -one of the three types of tissue that...

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