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Normal mouse urothelial organoids Basic Research
Nature Communications. A CNIO team uses organoid technology and single-cell RNA sequencing to advance in the study of bladder cancer Investigation of biological mechanisms in urothelial tissue -one of the three types of tissue that...
Un proyecto usará la luz para estudiar y tratar tumores y lesiones cerebrales Basic Research
A project to study and treat injury and tumours in the brain with light The Spanish National Cancer Research Centre (CNIO) and the Spanish National Research Council (CSIC)...
Follicular lymphoma Basic Research
Nature Metabolism. CNIO discovers a connection between nutrients and follicular lymphoma and tests a potential novel therapeutic approach Cancer deploys a vast array of resources to grow: from instability in its genome to inflammation, as...
Model of the role of TRF1 in controlling pluripotency Basic Research
eLife. A ‘butterfly effect’ discovered, through which a single change at telomeres controls the ability of cells to generate a complete organism Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to...
DAB haploids Basic Research
Cell Reports. CNIO researchers find a method to select for mammalian cells with half the number of chromosomes Since the emergence of molecular genetics more than fifty years ago, scientists have tried to...
Maria Blasco and Kurt Whittemore, CNIO Basic Research
PNAS. CNIO researchers discover that the rate of telomere shortening predicts species lifespan A flamingo lives 40 years and a human being lives 90 years; a mouse lives two years and an elephant...
Polycomb regions at mouse embryonic stem cells Basic Research
Cell Reports. CNIO researchers describe new functions of protein that plays key role in some tumours and rare diseases Cohesin is a protein complex that is essential for chromosome segregation in dividing cells. Recent...
Intestinal stem cells with URI, CNIO Basic Research
Science. CNIO researchers discover a new way to protect against high-dose radiation damage Radiotherapy, a common treatment for cancer, is one of the most effective ways to destroy cancer...
CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Basic Research
JNCI. CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Miguel Gallardo, researcher of the H12O-CNIO Haematological Malignancies Clinical Research Unit...