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Basic Research

Polycomb regions at mouse embryonic stem cells Basic Research
Cell Reports. CNIO researchers describe new functions of protein that plays key role in some tumours and rare diseases Cohesin is a protein complex that is essential for chromosome segregation in dividing cells. Recent...
Intestinal stem cells with URI, CNIO Basic Research
Science. CNIO researchers discover a new way to protect against high-dose radiation damage Radiotherapy, a common treatment for cancer, is one of the most effective ways to destroy cancer...
CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Basic Research
JNCI. CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Miguel Gallardo, researcher and coordinator of the H12O-CNIO Haematological Malignancies Clinical...
RUVBL1-RUVBL2 ring Basic Research
Science Advances. CNIO team describes the ‘energy engine’ mechanism of essential protein that mediates a variety of processes in cancer cells Proteins are sometimes described as the building blocks of life; inside cells proteins associate...
CNIO building Basic Research
Cancer Cell. CNIO researchers succeed at removing some types of pancreatic cancer in animal models Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National...
FAK activates cell migration Basic Research
PNAS. An international study co-led by CNIO identifies a ‘sensor’ that activates cell migration The cytoskeleton is a structure that not only helps cells maintain their shape and internal...
p62 Basic Research
Cancer Cell. Researchers from the CNIO and the Hospital 12 de Octubre make sense out of the chaos of melanoma Unlike other skin cancers – and without knowing really why – melanoma is one of the most...
Trombocitopenia-2 Basic Research
Journal of Clinical Investigation. CNIO finds the origin of a type of thrombocytopenia caused by an oncogene The Cell Division and Cancer Group of the Spanish National Cancer Research Centre (CNIO) has...
Basic Research
Nucleic Acids Research. An international team led by the CNIO reveals that human genome could contain up to 20% fewer genes A new study led by the Spanish National Cancer Research Centre (CNIO) reveals that up to 20% of...