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Image study breast cancer genes Translational
NEJM. The CNIO participates in a study that defines the most important genes that increase the risk of breast cancer Genetic inheritance affects the likelihood of developing breast cancer. Some genes are already known...
Long and short telomeres Basic Research
Aging. A CNIO study links severe COVID-19 disease to short telomeres Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study...
gTuRC Basic Research
Science Advances. Scientists from the CNIO and IRB Barcelona assemble the γ-tubulin ring complex in vitro for the first time Researchers from the Microtubule Organization lab, headed by Jens Lüders at IRB Barcelona, and the...
Clara Gómez-Aleza, Guillermo Yoldi and Eva González-Suárez Translational
Nature Communications. Scientists discover the immunomodulatory activity of a drug that would improve the efficacy of immunotherapy against breast cancer Despite the success of immunotherapy in the treatment of cancers such as lung or melanoma, it is...
Islet insulin glucagon, CNIO Basic Research
Cell Reports Medicine. A CNIO team describes how a virus can cause diabetes It has recently been described that infection by some enteroviruses – a genus of viruses that...
Marisol Soengas, David Olmeda, Daniela Cerezo, CNIO Basic Research
Nature Medicine. CNIO research team finds how melanoma deceives the immune system, increasing resistance to immunotherapy The sophisticated human immune system has evolved to become an effective protection system against a...
CRISPR and fusion genes Basic Research
Nature Communications. CNIO scientists succeed in reprogramming the CRISPR system in mice to eliminate tumour cells without affecting healthy cells The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of...
E-caderina and R-caderina in breast cancer Basic Research
CP&T. CNIO researchers identify genetic factors associated with the risk to develop hand-foot syndrome during chemotherapy with capecitabine Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend...
CDK4 and RAF1 inactivation Basic Research
PNAS. CNIO researchers develop an effective strategy to induce regression in lung tumours caused by the KRAS oncogene in mice The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are...