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Visualización del anidamiento de vesículas extracelulares de cáncer de próstata (verde) anidando en el hueso (rojo) por imagen de fluorescencia. Se observa que las vesículas llegan a órganos metastásicos típicos del cáncer de próstata. Héctor Peinado, Elena Castellano-Sanz / CNIO. Scientific News
Cancer Cell. Prostate cancer spreads by sending messages to other organs. An experimental technique hijacks them to monitor evolution of the disease and response to treatment Cells communicate with each other by releasing nanoparticles or vesicles filled with cellular...
From the left: Guadalupe Sabio, Héctor Pintado and Núria Malats. Credit: Laura M. Lombardía / CNIO. Scientific News
Why does obesity increase the risk of cancer and possibly metastasis? Three CNIO groups are investigating this very question Being obese or overweight increases the risk of developing several types of cancer, but the reason...
Ana Ortega-Molina, primary author and current researcher at the Severo Ochoa Molecular Biology Centre, and Alejo Efeyan, senior author, from the CNIO Metabolism and Cell Signalling Group. Credit: /CNIO. Basic Research
Nature Aging. Aging speeds up and lifetime becomes shorter in animals whose cells ‘believe’ to have too many nutrients, despite following a normal diet The reality of a population who is ageing at an accelerated rate makes it a priority to understand...
Scientific News
GUT. Strategy revealed that allows the most aggressive pancreatic cancer cells to evade the body’s defences Pancreatic cancer is usually diagnosed at an advanced stage and is highly resistant to chemotherapy....
Scientific News
World Melanoma Day. CNIO researchers explore new ways of attacking melanoma, an increasingly frequent cancer in which prevention is crucial In this video, the melanoma cells (in green) on the left have proteins that trick our defense system...
Novaseq X Plus sequencer Scientific News
CNIO will help to improve cancer prevention and personalized diagnosis with the most powerful ‘gene reader’ The most advanced DNA reading machine on the market, a sequencer capable of reading tens of...
Fluorescence microscopy visualization of melanoma cells. Basic Research
Cancer Communications. Combination of fasting and chemotherapy may improve cancer response, with different effects according to sex In recent years several research groups have found evidence, in animal models, that controlled...
María Martínez Molledo, first author of the study, an Óscar Llorca, senior coauthor. She is a researcher and he is the leader at the CNIO's Macromolecular Complexes in DNA Damage Response Group. Credit: Esther Sánchez / CNIO. Scientific News
Nature Communications. Neuronal ‘gateway’ for essential molecules in learning and memory observed at the atomic level Learning from an experience, remembering an anecdote, changing an attitude… all our behaviours...
Acumulación de “proteínas basura”: Células normales (izquierda) y células sometidas al efecto de la proteína tóxica rica en arginina (derecha). En esta se incrementan las proteínas ribosomales (verde fluorescente) y el tamaño de los nucléolos (rojo). Crédito: CNIO. Scientific News
Molecular Cell. Accumulation of ‘junk proteins’ identified as one cause of aging and possible source of ALS Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement...