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Follicular lymphoma Basic Research
Nature Metabolism. CNIO discovers a connection between nutrients and follicular lymphoma and tests a potential novel therapeutic approach Cancer deploys a vast array of resources to grow: from instability in its genome to inflammation, as...
Model of the role of TRF1 in controlling pluripotency Basic Research
eLife. A ‘butterfly effect’ discovered, through which a single change at telomeres controls the ability of cells to generate a complete organism Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to...
DAB haploids Basic Research
Cell Reports. CNIO researchers find a method to select for mammalian cells with half the number of chromosomes Since the emergence of molecular genetics more than fifty years ago, scientists have tried to...
Maria Blasco and Kurt Whittemore, CNIO Basic Research
PNAS. CNIO researchers discover that the rate of telomere shortening predicts species lifespan A flamingo lives 40 years and a human being lives 90 years; a mouse lives two years and an elephant...
Polycomb regions at mouse embryonic stem cells Basic Research
Cell Reports. CNIO researchers describe new functions of protein that plays key role in some tumours and rare diseases Cohesin is a protein complex that is essential for chromosome segregation in dividing cells. Recent...
Telomeres in mouse embryonic fibroblasts Innovation
EMBO Molecular Medicine. CNIO researchers find effective drug combinations for glioblastoma in mice Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it...
Intestinal stem cells with URI, CNIO Basic Research
Science. CNIO researchers discover a new way to protect against high-dose radiation damage Radiotherapy, a common treatment for cancer, is one of the most effective ways to destroy cancer...
CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Basic Research
JNCI. CNIO participates in an international study identifying hnRNP K as novel oncogene for most common types of blood cancer Miguel Gallardo, researcher and coordinator of the H12O-CNIO Haematological Malignancies Clinical...
RUVBL1-RUVBL2 ring Basic Research
Science Advances. CNIO team describes the ‘energy engine’ mechanism of essential protein that mediates a variety of processes in cancer cells Proteins are sometimes described as the building blocks of life; inside cells proteins associate...