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SolipPark-Figure-V1 Basic Research
Nature Communications. One mutation or two? Researchers in Spain discover why some genes require one or two hits to promote cancer The language in which the genome’s book of life is written is still being deciphered, which is...
El hematólogo Joaquín Martínez Translational
Journal of Hematology & Oncology. The CNIO and the Haematology Department of the Hospital 12 de Octubre identify a new factor that may have a positive impact on the survival of patients with multiple myeloma An international study led by the Haematology and Haemotherapy Department of the Hospital...
Structure of the LAT2/CD98hc protein Basic Research
PNAS. Spanish scientists determine the mode of action of essential proteins involved in cancer and Alzheimer´s disease The proteins that belong to the HAT family are essential for life as they transport amino acids...
CNIO researchers Héctor Peinado and Susana García Silva at the entrance of CNIO. Translational
Nature Cancer. CNIO researchers discover a new mechanism involved in early melanoma metastasis “We must not only look inside the tumour but also outside of it,” says Héctor Peinado, a...
Oncologist Joaquín Martínez (center in the first row) with his team from the H12O-CNIO Haematological Malignancies Clinical Research Unit and the Confocal Microscopy Unit led by Diego Megías (first left in the second row), which has also collaborated in the project. /Laura M. Lombardy. CNIO Translational
Blood Cancer Journal. Researchers at CNIO and 12 de Octubre Hospital prove efficacy of new immunotherapy for multiple myeloma CAR-T cell immunotherapy is a huge step forward in the treatment of blood cancer. However, it can...
Tumor pulmonar inducido por el KRAS4A. /CNIO Basic Research
PNAS. CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in human cancer KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common...
Alejo Efeyan and Ana Ortega, CNIO Basic Research
Cell Reports. CNIO researchers discover a new pathway to tackle follicular lymphoma For their own benefit and to grow beyond control, tumours manipulate cell signals to make it appear...
Estructura TELO2-TTI1-TTI2 complejo mTOR Basic Research
Cell Reports. CNIO researchers help to decipher the structure of the large molecular machine that assembles and activates mTOR The principle that form follows function does not only apply to design and architecture. It also...
De izquierda a derecha: Ana Belén-Plata Gómez, Alejo Efeyan y Nerea Deleyto-Seldas. /CNIO Basic Research
Nature Communications. A molecular switch that allows organisms to adapt to fasting conditions Getting energy and nutrients from the environment – that is, eating – is such an important...