Proteomics Core Unit

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Post-Doctoral Fellows

  • Francisco Javier Sánchez

Graduate Students

  • Cristina Sayago

Technicians

  • Fernando García
  • Jana Sánchez
  • Álvaro Soriano
  • Maria Pilar Ximénez de Embún
  • Eduardo Zarzuela

Proteins are the molecular effectors of cells and catalyse almost all biological processes. The levels of protein abundance, together with their modification states and interactions, adapt dynamically to external or internal ( genetic ) stimuli and thus define the cell’s functional state and determine its phenotype. Mass spectrometry-based proteomics is the most powerful tool to study the proteome, providing fundamental basic biology information. In addition, recent improvements in sensitivity and throughput now enable the analysis of larger cohorts of samples including biopsies, thereby making proteomics a part of the clinical research toolbox. All these efforts are providing new insights into the molecular mechanisms underlying cancer development as well as the identification of novel biomarkers.

Publications

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