Eva Ortega Director
T +34 917328000 (Ext 3650)
eortega@cnio.es

The main objective of CNIO Biobank is to facilitate access and distribution of human samples, ensuring that both the acquisition, maintenance and use complies with all the legal and ethical principles that protect donors’ rights. In this sense, a number of services are implemented, both for sample processing and for supporting different aspects of the management of collections and research projects.

Additionally, CNIO Biobank has its own R&D line and participates in several multicentric Biospecimen Science research projects.

The CNIO Biobank has been instrumental in the origin of collaborative biobanking modelling. In 2001 created the first collaborative network in Europe the CNIO Tumor Bank Network that sparked the development of international networks and European ESFRI in biobanking, BBMRI-ERIC . CNIO biobank has been the coordination node of the Spanish Biobank Network from its origins back in 2009 till 2018, an initiative of the Spanish Research Council, Instituto de Salud Carlos III, ISCIII.

Internationally, CNIO biobank leads and participates in numerous national and international forums, working groups and scientific societies. These include the presidency of the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB), Delegate at the International Society for Biological and Environmental Repositories (ISBER), international think tanks such as Marble Arch International Working Group on Clinical Biobanking, BC-Net IARC- WHO/NCI initiative, to name a few.

Publications

• Devereux L, Watson PH, Mes-Masson AM, Luna-Crespo F, Thomas G, Pitman H, Speirs V, Hall AG, Bollinger N, Posada M, Lochmüller H, Thorne H, Eng CB, Riegman PHJ, Ng W, Parry-Jones A (2019). A Review of International Biobanks and Networks: Success Factors and Key Benchmarks-A 10-Year Retrospective Review.. Biopreservation & Biobanking 17, 512-519. CNIO Publication.
• Esteva-Socias M, Artiga MJ, Bahamonde O, Belar O, Bermudo R, Castro E, Escámez T, Fraga M, Jauregui-Mosquera L, Novoa I, Peiró-Chova L, Rejón JD, Ruiz-Miró M, Vieiro-Balo P, Villar-Campo V, Zazo S, Rábano A, Villena C (2019). In Search of an Evidence-Based Strategy for Quality Assessment of Human Tissue Samples: Report of the Tissue Biospecimen Research Working Group of the Spanish Biobank Network. J Transl Med 17, 370. CNIO Publication. Open Access
• Zagorac I, Fernandez-Gaitero S, Penning R, Post H, Bueno MJ, Mouron S, Manso L, Morente MM, Alonso S, Serra V, Muñoz J, Gómez-López G, Lopez-Acosta JF, Jimenez-Renard V, Gris-Oliver A, Al-Shahrour F, Piñeiro-Yañez E, Montoya-Suarez JL, Apala JV, Moreno-Torres A, Colomer R, Dopazo A, Heck AJR, Altelaar M, Quintela-Fandino M (2018). In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer. Nat Commun 9, 3501. CNIO Publication. Open Access
• Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore HM, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M, Zaomi M, Zatloukal K, Dagher G (2017). Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.. Biopreservation & Biobanking 15, 270-276. CNIO Publication.
• Manso L, Mourón S, Tress M, Gómez-López G, Morente M, Ciruelos E, Rubio-Camarillo M, Rodriguez-Peralto JL, Pujana MA, Pisano DG, Quintela-Fandino M (2016). Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance.. PLoS ONE 11, e0155840. CNIO Publication.
• Suárez AE, Artiga MJ, Santonja C, Montes-Moreno S, De Pablo P, Requena L, Piris MA, Rodríguez-Pinilla SM (2016). Angioimmunoblastic T-cell lymphoma with a clonal plasma cell proliferation that underwent immunoglobulin isotype switch in the skin, coinciding with cutaneous disease progression.. J Cutan Pathol 43, 1203-1210. CNIO Publication.
• Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore H, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M, Zaomi M, Zatloukal K, Dagher G (2016). Annual Conference of the National Infrastructures for Biobanking. Biopreservation & Biobanking (in press). CNIO Publication.
• García-Donas J, Beuselinck B, Inglada-Pérez L, Graña O, Schöffski P, Wozniak A, Bechter O, Apellániz-Ruiz M, Leandro-García LJ, Esteban E, Castellano DE, González Del Alba A, Climent MA, Hernando S, Arranz JA, Morente M, Pisano DG, Robledo M, Rodriguez-Antona C. (2016). Deep sequencing reveals microRNAs predictive of antiangiogenic drug response.. JCI Insight 7, e86051. CNIO Publication.
• Riegman PH, de Jong B, Daidone MG, Söderström T, Thompson J, Hall JA, Mendy M, Ten Hoeve J, Broeks A, Reed W, Morente MM, López-Guerrero JA, Collins VP, Rogan J, Ringborg U (2015). Optimizing sharing of hospital biobank samples.. Sci Transl Med 7, fs31. CNIO Publication.
• Zapatero A, Morente M, de Vidales CM, Adrados M, Lopez C, Nieto S, González MJ, Arellano R, Conde AC, Vicente FG. (2015). HIF1A expression in localized prostate cancer treated with dose escalation radiation therapy.. Cancer Biomark 1, 41-46. CNIO Publication.
• Thomsen MK, Bakiri L, Hasenfuss SC, Wu H, Morente M, Wagner EF. (2015). Loss of JUNB/AP-1 promotes invasive prostate cancer.. Cell Death Differ 22, 574-582. CNIO Publication.

Biobank

CNIO Biobank (authorised by the Comunidad Autónoma de Madrid Health Department and registered in the National Registry of Biobanks with reference B.000848) is a ‘biobank for biomedical research purposes’, as defined by the Spanish Law 14/2007 and the Royal Decree RD 1716/2011. It´s therefore defined as a public, non-profit organization that hosts several human sample collections for biomedical research following quality and order criteria.