Biobank

Eva Ortega Director
T +34 917328000 (Ext 3650)
eortega@cnio.es

Technicians

Nuria Ajenjo
Inmaculada Almenara
María Jesús Artiga
Francisco De Luna

CNIO Biobank − authorised by the Health Authorities of the Comunidad Autónoma de Madrid (CAM) and registered in the National Registry of Biobanks with reference B.000848 − is a ‘biobank for biomedical research purposes’, as defined by the Spanish Law 14/2007 and the Royal Decree RD 1716/2011. It is therefore defined as a public, non-profit organisation that hosts several collections of human biological samples for biomedical research, specifically in cancer and related diseases. The main objective of the CNIO Biobank is to facilitate access to human samples for researchers, ensuring that both the acquisition and use of human samples complies with all the legal and ethical principles that protect donors’ rights.

In addition to this biobanking activity, a number of services have been implemented, both for sample processing and for supporting different aspects of the management of human samples for biomedical research, in order to facilitate the use of human samples for CNIO researchers.

CNIO Biobank is a founder member of the Spanish Biobank Network, a project funded by the Instituto de Salud Carlos III, ISCIII, currently through the Acción Estratégica en Salud – AES 2017 supportive platforms for research programmes. CNIO Biobank leads and/or participates in many different projects such as: centralised request management system (design and development); ethical, legal and social issues (ELSI); harmonisation; biospecimen science; and marketing plans.

Therefore, CNIO Biobank is a cross-service platform for CNIO researchers, as well as the general scientific community, and is geared towards the promotion of biomedical research in cancer and related diseases.

Publications

Romero-Blanco C, Artiga González MJ, Gómez-Cabello A, Vila-Maldonado S, Casajús JA, Ara I, Aznar S (2020). ACTN3 R577X Polymorphism Related to Sarcopenia and Physical Fitness in Active Older Women. Climacteric 30, 1-6. CNIO Publication.
Devereux L, Watson PH, Mes-Masson AM, Luna-Crespo F, Thomas G, Pitman H, Speirs V, Hall AG, Bollinger N, Posada M, Lochmüller H, Thorne H, Eng CB, Riegman PHJ, Ng W, Parry-Jones A (2019). A Review of International Biobanks and Networks: Success Factors and Key Benchmarks-A 10-Year Retrospective Review.. Biopreservation & Biobanking 17, 512-519. CNIO Publication.
Esteva-Socias M, Artiga MJ, Bahamonde O, Belar O, Bermudo R, Castro E, Escámez T, Fraga M, Jauregui-Mosquera L, Novoa I, Peiró-Chova L, Rejón JD, Ruiz-Miró M, Vieiro-Balo P, Villar-Campo V, Zazo S, Rábano A, Villena C (2019). In Search of an Evidence-Based Strategy for Quality Assessment of Human Tissue Samples: Report of the Tissue Biospecimen Research Working Group of the Spanish Biobank Network. J Transl Med 17, 370. CNIO Publication. Open Access
Zagorac I, Fernandez-Gaitero S, Penning R, Post H, Bueno MJ, Mouron S, Manso L, Morente MM, Alonso S, Serra V, Muñoz J, Gómez-López G, Lopez-Acosta JF, Jimenez-Renard V, Gris-Oliver A, Al-Shahrour F, Piñeiro-Yañez E, Montoya-Suarez JL, Apala JV, Moreno-Torres A, Colomer R, Dopazo A, Heck AJR, Altelaar M, Quintela-Fandino M (2018). In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer. Nat Commun 9, 3501. CNIO Publication. Open Access
Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore HM, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M, Zaomi M, Zatloukal K, Dagher G (2017). Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.. Biopreservation & Biobanking 15, 270-276. CNIO Publication.
Manso L, Mourón S, Tress M, Gómez-López G, Morente M, Ciruelos E, Rubio-Camarillo M, Rodriguez-Peralto JL, Pujana MA, Pisano DG, Quintela-Fandino M (2016). Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance.. PLoS ONE 11, e0155840. CNIO Publication.
Suárez AE, Artiga MJ, Santonja C, Montes-Moreno S, De Pablo P, Requena L, Piris MA, Rodríguez-Pinilla SM (2016). Angioimmunoblastic T-cell lymphoma with a clonal plasma cell proliferation that underwent immunoglobulin isotype switch in the skin, coinciding with cutaneous disease progression.. J Cutan Pathol 43, 1203-1210. CNIO Publication.
Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore H, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M, Zaomi M, Zatloukal K, Dagher G (2016). Annual Conference of the National Infrastructures for Biobanking. Biopreservation & Biobanking (in press). CNIO Publication.
García-Donas J, Beuselinck B, Inglada-Pérez L, Graña O, Schöffski P, Wozniak A, Bechter O, Apellániz-Ruiz M, Leandro-García LJ, Esteban E, Castellano DE, González Del Alba A, Climent MA, Hernando S, Arranz JA, Morente M, Pisano DG, Robledo M, Rodriguez-Antona C. (2016). Deep sequencing reveals microRNAs predictive of antiangiogenic drug response.. JCI Insight 7, e86051. CNIO Publication.
Riegman PH, de Jong B, Daidone MG, Söderström T, Thompson J, Hall JA, Mendy M, Ten Hoeve J, Broeks A, Reed W, Morente MM, López-Guerrero JA, Collins VP, Rogan J, Ringborg U (2015). Optimizing sharing of hospital biobank samples.. Sci Transl Med 7, fs31. CNIO Publication.
Zapatero A, Morente M, de Vidales CM, Adrados M, Lopez C, Nieto S, González MJ, Arellano R, Conde AC, Vicente FG. (2015). HIF1A expression in localized prostate cancer treated with dose escalation radiation therapy.. Cancer Biomark 1, 41-46. CNIO Publication.
Thomsen MK, Bakiri L, Hasenfuss SC, Wu H, Morente M, Wagner EF. (2015). Loss of JUNB/AP-1 promotes invasive prostate cancer.. Cell Death Differ 22, 574-582. CNIO Publication.

Biobank

CNIO Biobank (authorised by the Comunidad Autónoma de Madrid Health Department and registered in the National Registry of Biobanks with reference B.000848) is a ‘biobank for biomedical research purposes’, as defined by the Spanish Law 14/2007 and the Royal Decree RD 1716/2011. It´s therefore defined as a public, non-profit organization that hosts several human sample collections for biomedical research following quality and order criteria.