Grupo de Microambiente y Metástasis

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Becarios Post-doctorales

  • Marta Hergueta
  • Laura Nogués

Becarios Pre-Doctorales

  • Enrique Bastón
  • María Elena Castellano
  • Juan García-Agulló
  • Alberto Hernández

Técnicos de Laboratorio

  • Sara Sánchez-Redondo
  • Vanesa Santos

In the Microenvironment and Metastasis laboratory, we are interested in understanding the crosstalk between tumour and stromal cells along metastatic progression. We are especially interested in analysing the role of small extracellular vesicles (sEVs) in premetastatic niche formation in melanoma, pancreatic and prostate cancer. These particles reinforce tumour cell homing and metastasis in organs. Besides the role of sEVs, we are interested in understanding the influence of obesity and platelets in triple negative breast cancer and tumour metastasis in rare diseases such as follicular lymphoma and malignant peripheral nerve sheath tumours. Finally, we are defining new approaches to use circulating sEVs in liquid biopsies, analysing the use of mutations as indicators of minimal residual disease in melanoma and breast cancer.