Molecular imaging is a medical imaging modality that enables the visualisation, characterisation, and measurement of biological processes at the molecular and cellular levels within living organisms. This field of medical imaging combines principles from various disciplines, including chemistry, biology, physics, and imaging technology, to provide detailed information about the biochemical and physiological processes occurring in tissues and organs. Preclinical molecular imaging techniques are non-invasive, meaning they do not require the sacrifice or dissection of animals. This allows for longitudinal studies where researchers can monitor disease progression and treatment effects over time in the same animals.
The Molecular Imaging Unit provides the CNIO Research Groups with a range of advanced equipment and technologies that can be instrumental in early disease detection, monitoring disease progression, assessing the effectiveness of treatments, and gaining a deeper understanding of disease mechanisms at the molecular level. This support is crucial for advancing medical research and improving patient care.
Publicaciones
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Salmón M, Álvarez-Díaz R, Fustero-Torre C, Brehey O, Lechuga CG, Sanclemente M, Fernández-García F, López-García A, Martín-Guijarro MC, Rodríguez-Perales S, Bousquet-Mur E, Morales-Cacho L, Mulero F, Al-Shahrour F, Martínez L, Domínguez O, Caleiras E, Ortega S, Guerra C, Musteanu M, Drosten M, Barbacid M. (2023).Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas.. J Clin Invest 133, e164413. Publicación CNIO. Open Access
Martínez-Illescas NG, Leal S, González P, Graña-Castro O, Muñoz-Oliveira JJ, Cortés-Peña A, Gómez-Gil M, Vega Z, Neva V, Romero A, Quintela-Fandino M, Ciruelos E, Sanz C, Aragón S, Sotolongo L, Jiménez S, Caleiras E, Mulero F, Sánchez C, Malumbres M, Salazar-Roa M (2023).miR-203 drives breast cancer cell differentiation. Breast Cancer Res 25, 91. Publicación CNIO. Open Access
Open Access