One of the greatest challenges in oncology research is the detailed study of specific markers, expression patterns, and individual cells in the tumour and its microenvironment. Optical microscopy has become a key technology in the field to boost our understanding of the cellular and molecular mechanisms driving cancer, as well as to explore potential therapeutic strategies.
The Confocal Microscopy Unit (CMU) provides scientific advice and technical support through cutting-edge imaging technologies, focusing on cancer biology and other biomedical research areas. CNIO research groups have access to state-of-the-art equipment and a High-end BioImage Analysis platform.
Our team is also dedicated to the development and implementation of innovative imaging techniques that can have an impact on CNIO scientific projects. Training and science dissemination are key elements of our mission. We organise courses, seminars, and lab visits aimed at advancing optical microscopy culture.
Chatterjee S, Hofer T, Costa A, Lu D, Batkai S, Gupta SK, Bolesani E, Zweigerdt R, Megias D, Streckfuss-Bömeke K, Brandenberger C, Thum T, Bär C. (2021).Telomerase therapy attenuates cardiotoxic effects of doxorubicin.. Mol Ther 29, 1395-1410. Publicación CNIO.
Leivas A, Valeri A, Córdoba L, García-Ortiz A, Ortiz A, Sánchez-Vega L, Graña-Castro O, Fernández L, Carreño-Tarragona G, Pérez M, Megías D, Paciello ML, Sánchez-Pina J, Pérez-Martínez A, Lee DA, Powell DJ Jr, Río P, Martínez-López J (2021).NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma. Blood Cancer J 11, 146. Publicación CNIO.
