The functions of many proteins, particularly those associated with cancer, remain poorly understood. Progress in biomedical research depends on determining protein structures, defining their distribution within cells and tissues, and elucidating their biological roles. A major bottleneck, however, is the difficulty of producing proteins of interest in sufficient quality and quantity for comprehensive analysis, which hampers research progress.
The Protein Production Unit was established to address this limitation. This core facility provides specialised expertise and advanced technologies to develop efficient pipelines for the production of high-quality recombinant proteins. These proteins are essential resources for a variety of downstream applications, including the generation of highly specific antibodies, biophysical and biochemical characterisation, functional assays, and structural studies. Ultimately, the Unit aims to accelerate cancer research at CNIO and support external research groups.
Publicaciones recientes
Garaulet G, Báez BB, Medrano G, Rivas-Sánchez M, Sánchez-Alonso D, Martinez-Torrecuadrada JL, Mulero F. (2024).Radioimmunotheragnosis in Cancer Research. Cancers 16, 2896. Publicación CNIO.
Open Access