The biological functions of many proteins, especially those involved in cancer, still remain uncharted. Understanding their structures, tissue and cellular distributions, and functions is critical for biomedical progress. However, researchers often encounter the challenge of insufficient supply, as proteins of interest identified in a specific process can be very difficult to produce in high quality and quantity for analysis. This bottleneck hinders the pace at which they can be characterised. The Protein Production Unit is a core lab designed to address this issue. It offers expertise and state-of-the-art technologies to develop efficient processes for producing recombinant proteins. These proteins can be utilised in various downstream applications, including to generate highly specific antibodies, biophysical, biochemical or functional analyses, as well as structural studies. The ultimate goal is to accelerate cutting-edge cancer research for CNIO and external research groups.
Publicaciones
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Garaulet G, Báez BB, Medrano G, Rivas-Sánchez M, Sánchez-Alonso D, Martinez-Torrecuadrada JL, Mulero F. (2024).Radioimmunotheragnosis in Cancer Research. Cancers 16, 2896. Publicación CNIO.
Open Access