Our lab specializes in protein design, structural biology, and synthetic biology, leveraging AI-driven approaches to engineer protein cages, nanomachines, and other biomolecules with precise functions. By combining these innovations with detailed studies of viral structures, we explore new ways to manipulate biological systems.
Our goal is to translate these advances into nanomedicine, developing cutting-edge tools and therapeutic platforms that address critical challenges in cancer and human health.
Castells-Graells R, Hesketh EL, Matsui T, Johnson JE, Ranson NA, Lawson DM, Lomonossoff GP (2024).Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM.. BioRxiv (in press). Publicación en otras instituciones.