Título/Title: Clinical qualification of DNA repair defects as prognostic and predictive biomarker in metastatic prostate cancer using genomics and tissue-based functional assays
Ref.: W81XWH-18-1-0770
Investigador Principal/Principal Investigator: Olmos Hidalgo, David
Fecha Inicio/Starting Date: 30/09/2018
Fecha Fin/Ending Date: 29/09/2022
Presupuesto/Budget: $ 769.322,00
Información adicional/Other information: Prostate Cancer Research Program (PCRP)

Título/Title: Defining the role of exosome-secreted Endoglin in NF1 progression, a potential new target
Ref.: W81XWH-16-1-0131
Investigador Principal/Principal Investigator: Peinado Selgas, Héctor
Fecha Inicio/Starting Date: 01/07/2016
Fecha Fin/Ending Date: 30/09/2020
Presupuesto/Budget: $ 463.862,00
Información adicional/Other information: Neurofibromatosis Research Program

Título/Title: Role of the smooth muscle layer in bladder cancer biology and progression: a systems and experimental approach
Ref.: R21CA266660
Investigador Principal/Principal Investigator: Real Arribas, Francisco
Fecha Inicio/Starting Date: 13/12/2022
Fecha Fin/Ending Date: 31/08/2024
Presupuesto/Budget: $138.763,00
Información adicional/Other information: Research Project Grant Program. Collaborative project that is coordinated by Joan and Sanford I Weill Medical College of Cornell University

Título/Title: Targeting Mdm2-MdmX E3 ligase for treatment of drug-rresistant lymphoma
Ref.: R01CA208352
Investigador Principal/Principal Investigator: Muñoz Fernández, Inés G.
Fecha Inicio/Starting Date: 01/04/2017
Fecha Fin/Ending Date: 31/03/2022
Presupuesto/Budget: $170.409,00
Información adicional/Other information: Research Project Grant Program. Collaborative project that is coordinated by HEALTH RESEARCH, INC. Only CNIO Budget for years 1 to 5 is here shown

Título/Title: GENCODE: comprehensive gene annotation for human and mouse
Ref.: U41 HG007234
Investigador Principal/Principal Investigator: Tress, Michael
Fecha Inicio/Starting Date: 01/04/2013
Fecha Fin/Ending Date: 30/06/2025
Presupuesto/Budget: $ 477.338,08
Información adicional/Other information: Genomic resource Grants for Community Resource Projects (U41) PAR-11-095. Only CNIO Budget for years 9 to 12 is here shown

Título/Title: Defining the role of obesity in the regulation of disseminated tumor cell homing and dormancy
Ref.: 24-0197
Investigador Principal/Principal Investigator: Peinado Selgas, Héctor
Fecha Inicio/Starting Date: 01/03/2024
Fecha Fin/Ending Date: 28/02/2027
Presupuesto/Budget: £233.700,00
Información adicional/Other information:

Título/Title: Exploring the use of CDK4/6 inhibitors in combination with classical
chemotherapy
Ref.: 20-0155
Investigador Principal/Principal Investigator: Malumbres Martínez, Marcos
Fecha Inicio/Starting Date: 01/07/2020
Fecha Fin/Ending Date: 30/06/2023
Presupuesto/Budget: £232.500,00

Título/Title: S100A9-dependent radiation resistance in brain metastasis
Ref.: 19-0177
Investigador Principal/Principal Investigator: Valiente Cortés, Manuel
Fecha Inicio/Starting Date: 01/01/2019
Fecha Fin/Ending Date: 31/03/2022
Presupuesto/Budget: £151.884,09
Información adicional/Other information:

Título/Title: Targeting telomeres in cancer
Ref.: 16-1177
Investigador Principal/Principal Investigator: Blasco, Maria A.
Fecha Inicio/Starting Date: 01/06/2016
Fecha Fin/Ending Date: 31/05/2019
Presupuesto/Budget: £249.999,00
Información adicional/Other information:

Título/Title: Evaluation of obesity as a novel risk factor in metastasis
Ref.: 16-1244
Investigador Principal/Principal Investigator: Peinado Selgas, Héctor
Fecha Inicio/Starting Date: 01/06/2016
Fecha Fin/Ending Date: 31/05/2019
Presupuesto/Budget: £188.810,00
Información adicional/Other information:

Título/Title: Discovering novel molecular nodes involved in MTC development and evolution
Ref.: GRANT2020-0000000150
Investigador Principal/Principal Investigator: Montero, Cristina
Fecha Inicio/Starting Date: 01/07/2020
Fecha Fin/Ending Date: 30/06/2022
Presupuesto/Budget: $ 50.000,00
Información adicional/Other information: Thyroid Research Grant Program , cofunded by Bite Me Cancer (BMC) and the American Thyroid Association (“ATA”)

Título/Title: Brain-specific strategies to improve responses to immunotherapy
Ref.: 54545
Investigador Principal/Principal Investigator: Valiente Cortés, Manuel
Fecha Inicio/Starting Date: 01/07/2018
Fecha Fin/Ending Date: 30/06/2021
Presupuesto/Budget: $198.700,00
Información adicional/Other information:

Título/Title: Elucidating mechanisms of epigenetic changes in type 1 diabetes and treatment with DNA demethylating drugs
Ref.: –
Investigador Principal/Principal Investigator: Djouder, Nabil
Fecha Inicio/Starting Date: 01/01/2019
Fecha Fin/Ending Date: 30/11/2020
Presupuesto/Budget: 100.000,00 €
Información adicional/Other information:

Título/Title: Photochemical trap and high-resolution imaging of transient chromatin complexes from living cells
Ref.: RGP0031/2017
Investigador Principal/Principal Investigator: Llorca Blanco, Óscar
Fecha Inicio/Starting Date: 01/12/2017
Fecha Fin/Ending Date: 30/11/2021
Presupuesto/Budget: $420.000,00
Información adicional/Other information: HFSP Research Grants

Título/Title: Identification of genomic and immune factors in high-risk populations for pancreatic cancer
Ref.: –
Investigador Principal/Principal Investigator: Malats Riera, Núria
Fecha Inicio/Starting Date: 15/05/2019
Fecha Fin/Ending Date: 31/10/2021
Presupuesto/Budget: $ 1.000.000,00
Información adicional/Other information: Total project budget. Collaborative project coordinated by University of Columbia.

Título/Title: Chemical hijacking of E3 ligases for the selective targeting of oncogenic mTOR signaling
Ref.: –
Investigador Principal/Principal Investigator: Efeyan, Alejo
Fecha Inicio/Starting Date: 01/03/2023
Fecha Fin/Ending Date: 31/12/2023
Presupuesto/Budget: $ 249.997,00
Información adicional/Other information: ASPIRE project. Total project budget. Collaborative project coordinated by IRB-Barcelona

Título/Title: Deconstructing the biology of local relapse post-surgery to develop novel preventive strategies in brain metastasis
Ref.: –
Investigador Principal/Principal Investigator: Valiente Cortés, Manuel
Fecha Inicio/Starting Date: 01/12/2021
Fecha Fin/Ending Date: 30/11/2022
Presupuesto/Budget: $ 251.576,00
Información adicional/Other information: ASPIRE project

Título/Title: Blocking melanoma brain metastasis by targeting the microenvironment
Ref.: 498103
Investigador Principal/Principal Investigator: Valiente Cortés, Manuel
Fecha Inicio/Starting Date: 15/05/2017
Fecha Fin/Ending Date: 17/11/2020
Presupuesto/Budget: $225.000,01
Información adicional/Other information: MRA Young Investigator Award

Título/Title: Imaging and targeting dormant and pro-metastatic melanoma lesions in vivo
Ref.: 401181
Investigador Principal/Principal Investigator: Soengas González, María S.
Fecha Inicio/Starting Date: 15/05/2016
Fecha Fin/Ending Date: 14/05/2019
Presupuesto/Budget: $900.000,00
Información adicional/Other information: Team Science Award

Título/Title: Integration of multi-omics profiling and immune contexture in metastatic PPGL patients
Ref.: –
Investigador Principal/Principal Investigator: Robledo Batanero, Mercedes; Al-Shahrour, Fátima
Fecha Inicio/Starting Date: 01/01/2020
Fecha Fin/Ending Date: 31/12/2022
Presupuesto/Budget: 344.416,00 €
Información adicional/Other information:

Título/Title: Prospective study of lethal prostate cancer clinical and genomic evolution in DNA repair deficient tumours
Ref.: –
Investigador Principal/Principal Investigator: Castro Marcos, Elena
Fecha Inicio/Starting Date: 10/07/2017
Fecha Fin/Ending Date: 30/06/2021
Presupuesto/Budget: $225.000,00
Información adicional/Other information: PCF Young Investigator Award