Unidad de Citogenética Molecular

Inicio | Investigación e innovación | Programas Científicos | Programa de Genética del Cáncer Humano | Unidad de Citogenética Molecular

Sandra Rodríguez
Sandra Rodríguez Jefe de Unidad
T +34 917328000 (Ext 3340)
srodriguezp@cnio.es

Investigadores

  • Raúl Torres

Becarios Pre-Doctorales

  • Pilar Puig

Técnicos de Laboratorio

  • M. Carmen Martín
  • Marta Martínez-Lage
  • Francisco José Moya

Recurrent chromosomal rearrangements − changes in the structure of native chromosomes − are very common and wellknown hallmarks of cancer. Recent technological advances have improved our ability to detect and understand these rearrangements. A better understanding of these cancercausing mechanisms will lead to novel therapeutic regimens to fight cancer. The research activity of the Molecular Cytogenetics and Genome Editing Unit focuses on increasing the knowledge about the role of chromosomal rearrangements in cancer development and progression and the discovery of new therapeutic targets. With the combined use of CRISPR genome editing and cytogenetic technologies, we are creating in vitro models that recapitulate chromosomal, genetic, and epigenetic cancer alterations. The goal of the Unit is to provide the CNIO and external researchers with the latest technologies used in the fields of molecular cytogenetics and genome engineering. The Unit is continuously implementing and developing new technologies in those fields. We also participate in collaborative projects with clinical and basic science investigators at the CNIO and other institutions.

Publicaciones

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