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Structural Biology Programme

Crystallography and Protein Engineering Unit

Head of Unit:  Inés Muñoz
Overview

The Crystallography and Protein Engineering Unit (XTPEUnit) is a central core facility as well as a research laboratory; its main goal is to fulfil the requests of research groups at the CNIO and outside our Centre, by providing on-demand services at different levels. These services range from the production of recombinant proteins for different types of biochemical/biophysical assays and monoclonal antibody production, to macromolecular structural determination at low resolution by small-angle X-ray scattering (SAXS), or at high resolution by X-ray crystallography. The latter includes co-crystallisation in the presence of inhibitors, during the guided drug design process.