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Clinical Research Programme

H12O - CNIO Haematological Malignancies Clinical Research Unit

Head of Unit:  Joaquín Martínez
Overview

The Haematological Malignancies Clinical Research Unit focuses on 3 main objectives:

  • Molecular research of haematological cancers: studying of cancer induced changes at the proteomic and genomic levels. We aim to: i) find new genomic and proteomics biomarkers for a better diagnosis of these haematological diseases; ii) detect new molecular alterations as predictors of response to a treatment, for example by studying minimal residual disease; and iii) study immune mechanisms of cancer control, with a special focus on NK cells.
  • In vitro & in vivo research: i) to establish the effects of new anticancer molecules in in vitro models of the disease; ii) to determine the mechanisms of resistance to anticancer drugs.
  • Clinical research: translate preclinical findings to the patients through a phase I clinical trials unit.