Biotechnology Programme

Molecular Imaging Core Unit

Head of Unit:  Francisca Mulero
Overview

Molecular Imaging (MI) enables the visualisation of cellular function and the follow-up of molecular processes in living organisms without perturbing them. Molecular imaging offers significant advantages to the scientist over traditional research paradigms. While traditional studies of tumour response to a therapeutic agent involve a large cohort of animals analysed at multiple time points, molecular imaging allows characterisation of tumour development and response to a therapy within the same small set of animals imaged longitudinally at multiple time points, thereby reducing the number of mice and also increasing the statistical power of the study because each animal serves as its own control. Other advantages of molecular imaging procedures include the ability to interrogate the whole body, and to visualise the molecular target of interest in 3-dimensional space. Finally, Molecular Imaging is becoming a key bridging technology for the translation of experimental preclinical findings into the clinical environment