• CNIO team turns tumour suppressor into anti-cancer target
  04.12.2013
  The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre’s (CNIO) Cell Division & Cancer Group, working alongside Isabel Fariñas’ team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein—a sub-unit of the APC/C […]
• Four years of clinical trials at the CNIO
  02.12.2013
  Madrid (Spain), December 2, 2013.Four years ago, the Spanish National Cancer Research Centre (CNIO) embarked on a new quest with the creation of its Clinical Research Programme. This Programme was financed in part with a 12 million euro credit loan from the Ministry of Health, which was distributed between 2009 and 2011. The goal of […]
• CNIO scientists create the first large catalogue of interactions between drugs and proteins
  28.11.2013
  The three-dimensional structures of proteins determine how, when and where they bind to drugs and other compounds. In 2012 alone, thousands of structures like this were resolved. Now this mass of information needs to be translated into a biological context that can be used to extract relevant functions from these interactions, as well as significant […]
• CNIO and the Jesús Serra Foundation renew their commitment to the Visiting Scientists Programme
  26.11.2013
  CNIO AND THE JESÚS SERRA FOUNDATION RENEW THEIR COMMITMENT TO THE VISITING SCIENTISTS PROGRAMME>The Spanish National Cancer Research Centre (CNIO) and the Jesús Serra Foundation have renewed their collaborative agreement for the Visiting Scientists Programme, in order to deepen the scientific relationship between both organisations and to open up the possibilty of beginning new lines […]
• Spanish scientists identify a new ancestral enzyme that facilitates DNA repair
  20.11.2013
  Every day, the human body produces new cells to regenerate tissues and repair those that have suffered injury. Each time this happens, the cells make copies of their DNA that they will pass on to the resulting daughter cells. This process of copying the DNA, also called replication, is very delicate, given that it can […]
• A CNIO study recreates the history of life through the genome
  18.11.2013
  One of the most important processes in the life of cells is genome replication, which consists of making exact copies of the DNA in order to pass it on to their offspring when they split. In most organisms, from yeast to human beings, genome replication follows a set plan, in which certain regions of the […]
• A study led by the CNIO validates a new anti-cancer therapy based on cell division
  15.11.2013
  Aurora-A is a protein involved in the cell division process that is highly expressed or synthesised in a large number of human cancers, especially in those associated with a bad prognosis. Several pharmaceutical companies have recently developed these protein inhibitors, although the therapeutic and physiological effects that blocking Aurora-A might have on adult tissues are […]
• A CNIO team discovers that senescence also plays a role in embryo development
  14.11.2013
  One of the main mechanisms the body uses to protect itself against cancer is to switch off defective cells by making them senescent; these cells do not die but stop dividing: their life cycle stops. A team of researchers from the Spanish National Cancer Research Centre (CNIO) in Madrid and another one from the Centre […]
• CNIO scientists decipher how the immune system induces liver damage during hepatitis
  08.11.2013
  Viral infections are the primary cause of liver inflammation or hepatitis, affecting hundreds of millions of people all over the world, and they represent a public health problem worldwide. The acute condition can cause irreversible damage to the liver, and if not cured can become chronic, leading to serious diseases such as cirrhosis or cancer.A […]