- CNIO researchers discover a molecular mechanism that initiates colon cancer
06.05.2025
Colorectal – colon or rectal – cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or excessive alcohol consumption. Most colorectal cancers arise from adenomatous polyps, a precancerous lesion that may progress to a […] - The CNIO will use AI to search for mutation patterns which help predict tumor development and response to treatment
16.04.2025
Some tumors are caused by one or more inherited mutations in specific genes. Others are the result of the accumulation, over a lifetime, of mutations induced by environmental factors or lifestyle habits. Over time, research has identified some of these mutations as being directly responsible for causing a tumor. However, there are many other mutations […] - Two new research groups at CNIO thanks to the arrival of the ‘AI Generation’
09.04.2025
The ministry for Digital Transformation and Public Service and the ministry of Science, Innovation and Universities presented the programme ‘Generation D: Building the AI Generation’, which has allowed the National Cancer Research Centre (CNIO) to bring on board two new research groups and fourteen researchers. They all share the ability to use Artificial Intelligence as […] - CNIO research reveals how melanoma and other tumours succeed in hiding and resisting immunotherapy
28.03.2025
Cutaneous melanoma, the most aggressive form of skin cancer, is characterised by its accumulation of a large number of mutations. Although some of these alterations should be recognised as a threat by our defences, melanomas often escape immune system surveillance. As a result, more than half of patients do not generally respond to current immunotherapies. […] - CNIO researchers discover a new mechanism for rapid liver regeneration triggered by glutamate
26.03.2025
The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that these cells eliminate. However, the liver stops regenerating in cases of diseases that involve chronic liver damage –such as cirrhosis–. Such […] - Curing cancer? Research is where it all begins
25.03.2025
At the Spanish National Cancer Research Center, the CNIO, we do research to learn how to reduce the risk of cancer; detect it as early as possible; and treat it effectively. We know that it is not easy, and that we will come forward little by little. But we are convinced that our work, research, […] - CNIO research on lung, skin and pancreatic cancer receives funding from the Spanish Association Against Cancer
18.02.2025
The search for new treatments against the most aggressive lung cancer, malignant melanoma and pancreatic cancer, the possibility of using nutrition against metastasis, the study of resistance to targeted therapies for melanoma, and the development of therapies based on tumor nutrients are projects at the Spanish National Cancer Research Center (CNIO) selected for the grants […] - CNIO researchers seek more effective immunotherapies for children with cancer
14.02.2025
Pediatric cancer is relatively rare, yet it is the leading cause of death by disease in children and teenagers in the developed world. It is different from adult cancer and therefore requires research and specific therapies. But for pediatric patients treatments are not improving at the same rate as for the rest, recalls Antonio Pérez-Martínez, […] - Female researchers at CNIO ‘talk’ to the girls they once were
11.02.2025
‘I know you have plenty of doubts’, ‘trust yourself’, ‘don’t worry if you are told to ask too many questions.’ Six female researchers who currently work at the main Spanish public center for cancer research, the National Cancer Research Centre (CNIO), recall the girls they once were in the hope to reach out to the […]