Grupo de Microambiente y Metástasis

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Hector Peinado
Hector Peinado Heads of Research Units
T +34 917 328 000 (Ext 3520)
hpeinado@cnio.es

Staff Scientists

Post-Doctoral Fellows

  • Marta Hergueta
  • Laura Nogués

Graduate Students

  • Ana Isabel Amor
  • María Teresa González
  • Alberto Hernández
  • Lucía Robado

Technicians

  • Marina Mazariegos
  • Sara Sánchez-Redondo

Our laboratory is interested in analysing the main mechanisms involved in tumour-microenvironment communication during metastasis. Extracellular vesicles (EVs) and soluble factors are key players during this process. Tumour cells benefit from the secretion of these factors partly by influencing the behaviour of neighbouring cells in the tumour microenvironment. We are exploring the role of secreted factors and vesicles in metastasis using different approaches: 1) decoding the messages packaged in tumour-derived exosomes during melanoma metastasis, 2) defining novel factors involved in the crosstalk between adipose tissue and tumour, and 3) testing new therapies to prevent metastasis in rare diseases such as neurofibromatosis.

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