Transformation and Metastasis Group

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Eva González Suárez
Eva González Suárez Group Leader
T +34 (+34) 917 328 000 (Ext 3550)

Staff Scientists

  • Patricia González
  • María Jiménez
  • Gema Pérez

Graduate Students

  • Alexandra Barranco
  • Marina Císcar
  • Alejandro Collado
  • Jaime Redondo

Current therapies for breast cancer and other epithelial tumours are in many cases not effective because of intrinsic or acquired resistance, and tumours often relapse, leading to metastatic disease.

Research in the Transformation and Metastasis Group aims to identify novel therapeutic targets for cancer prevention and treatment, and to elucidate resistance mechanisms to drugs currently available. Tumours exploit and manipulate for their benefit the same mechanisms that work correctly in healthy tissue. Thus, we first aim to understand normal development and identify the key events that lead to tumour initiation, progression and metastasis to avoid and combat them. We work with primary cell cultures (including 3D cultures), genetically modified mouse models, patient derived xenografts and clinical samples.

The main contributions of the Group are within the field of mammary gland biology and breast cancer. Our goal is to translate our basic research findings into relevant clinical results.