Home | Research & Innovation | Scientific Programmes | Molecular Oncology Programme | Transformation and Metastasis Group

Eva González
Eva González Group Leader
T +34 912246912 (Ext 3550)

Staff Scientists

  • María Jiménez

Graduate Students

  • Marina Císcar

Current therapies for breast cancer and other epithelial tumors are in many cases not effective because of intrinsic or acquired resistance and tumors often relapse leading to metastatic disease. Research in the Transformation and Metastasis group aims to identify novel therapeutic targets for cancer prevention and treatment and to elucidate resistance mechanisms to drugs currently available. Tumors exploit and manipulate for their benefit the same mechanisms that work correctly in the healthy tissue. Thus, we first aim to understand normal development and identify the key events that lead to tumor initiation, progression and metastasis to avoid and combat them. We work with primary cell cultures (including 3D) cultures, genetically modified mouse models, patient derived xenografts and clinical samples.