Cell Division and Cancer Group

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Marcos Malumbres
Marcos Malumbres Group Leader
T +34 917328000 (Ext 3450)
mmm@cnio.es

Staff Scientists

  • Mónica Álvarez

Post-Doctoral Fellows

  • Begoña Hurtado
  • Carolina Maestre
  • María Salazar
  • Carolina Villarroya

Graduate Students

  • José González
  • Diego Martínez

Technicians

  • Aicha El Bakkali
  • Elisabet Zapatero

The Cell Division and Cancer Group is interested in deciphering the mechanisms by which cell division and cell proliferation are regulated in mammalian cells. During the last years, we have used different mouse models to understand the relevance of cell cycle regulators, including cell cycle kinases and phosphatases, as well as proteins involved in ubiquitin-dependent degradation, in the control of cell division and tissue physiology.

Our interests are:

  1. To understand the basic control mechanisms that regulate the cell division cycle.
  2. To characterise the physiological and therapeutic consequences of cell cycle deregulation.
  3. Understanding self-renewal and pluripotency in stem cell biology and tumour development.
  4. To find and validate new targets for cancer therapy. As a final goal, we aim to generate information that may be useful to improve therapeutic strategies against cancer cell proliferation.

Publications

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