Haematological clinical research has traditionally focused on haematological malignancies, aplasia and syndromes. Now, with advances in immunotherapy, haematologists play a key role in research on novel immunotherapeutic approaches, the role of the immune response to tumours, or the role of infection and inflammation in cancer.
In the Haematological Malignancies Clinical Research Unit at CNIO we investigate:
- Traditional haematological neoplasms (leukaemia, myeloma, lymphoma): new diagnostic approaches, biomarkers, and treatments.
- Aplastic haematological malignancies such as bone marrow failures: new drivers and molecular mechanisms.
- Novel diagnosis and tumour burden monitoring: liquid biopsy and minimal residual disease.
- Role of inflammation and infection in haematological neoplasms.
- Novel immunotherapeutic approaches in haematological malignancies: NK-CARs, BITES.
- Traditional immunotherapeutic approaches in haematological malignancies and paediatric cancers: T-CARs and immune checkpoints inhibitors.