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Alejo Efeyan, head of the Metabolism and Cell Signalling Group in his lab at CNIO Basic Research
18.03.2024
Nature Communications. Discontinuous food intake activates a ‘GPS gene’ in liver cells, thus completing the development of the liver after birth In mammals, the liver detects the body’s energy demand at any given moment and mobilizes...
Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in which the molecule is being copied. The distance between the ends of the white arrows is about 100 thousandths of a millimeter (µM); it corresponds to 250,000 'letters' of DNA (bases). / Sara Rodríguez-Acebes. CNIO Basic Research
04.03.2024
The EMBO Journal. CNIO researchers discover a protein that prevents DNA triplication Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same...
Germinal center with normal structure on the left and aberrant due to lack of NGFR on the right. The maturing B lymphocytes are shown in green and the cells that generate the structure in red /Alberto Hernández. CNIO Basic Research
26.02.2024
Cell Reports. The molecule behind a potential new therapy for melanoma also plays a key role in autoimmune diseases Three years ago, in 2021, the Microenvironment and Metastasis Group at the Spanish National Cancer...
Translational
14.02.2024
Science Translational Medicine. New immunotherapy for multiple myeloma proves in the lab to be more effective than CAR-T treatment already in use Immunotherapy is already improving treatment options for many cancer types, but research groups keep...
Basic Research
02.02.2024
Science. First atomic-scale ‘movie’ of microtubules under construction, a key process for cell division Cells in the human body are constantly dividing. With each division the genetic information...
Scientific News
25.01.2024
Science Advances. A virus that infected the first animals hundreds of millions of years ago has become essential for the development of the embryo All animals have evolved thanks to the fact that certain viruses infected primitive organisms...
Los investigadores del CNIO Héctor Peinado y Nùria Malats, con el coordinador de PANCAID, Klaus Pantel, en el centro. Translational
22.01.2024
The search for a liquid biopsy for the early detection of pancreatic cancer summons top European experts in this tumor at the CNIO Pancreatic cancer is usually detected in advanced stages, often resulting in death within a year of...
Translational
19.01.2024
Haematologica. The case of a patient with multiple myeloma cured after hepatitis treatment reveals that this cancer can be caused by viruses, and opens up new treatment options A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C,...
Scientific News
15.01.2024
Genome Medicine. 103 genes that cause inherited diseases when mutated can also increase cancer risk About one hundred so-called cancer predisposition genes (CPGs) are known. The probability of...

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