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Public announcement of SOSCLC – AECC project /AECC
It involves 40 research groups from all over Spain, coordinated by Luis Paz-Ares (CNIO-Hospital 12 de Octubre) and Marcos Malumbres (VHIO)
The AECC is funding the network with 10 million euros over five years
Smoking is the main risk factor for lung cancer. The most aggressive type of this tumor, small cell lung cancer, is often diagnosed once it has already spread, in which case only 3% of patients live longer than five years. A large project involving more than 300 researchers from all over Spain is now seeking to improve the survival and quality of life of patients with this cancer.
The project, called SOSCLC-AECC: Small cell lung cancer. From biological networks to personalized therapy, is funded by the Spanish Association Against Cancer (AECC) with 10 million euros over five years. It is coordinated by Luis Paz-Ares, head of the H12O-CNIO Lung Cancer Clinical Research Unit, and Marcos Malumbres, since 2004 head of the Cell Division and Cancer Group at the CNIO and currently at the Vall d’Hebron Institute of Oncology (VHIO).
It involves 40 research groups from A Coruña, Barcelona, Bilbao, Cádiz, Huelva, Las Palmas, Madrid, Málaga, Murcia, Oviedo, Pamplona, Salamanca, Sevilla, Valencia and Zaragoza. They are clinical groups with experience in coordinating clinical trials, and preclinical research groups which include experts in novel therapeutic approaches (epigenetics, molecular glues, miniproteins, new immunotherapies) and computational scientists.
The main goal of the project is to improve the survival and quality of life of patients with SCLC. To this end, the distribution and risk factors of this cancer in Spain will be studied, cellular alterations and how tumors evade the immune system will be analyzed, and patients will be involved in the research. The aim is also to raise social awareness of the disease.
According to the AECC, patients will be represented by a Patient Advocate, and there will be patient contact points distributed throughout the country. External collaborators will contribute their expertise in the biology and clinical management of lung cancer. The Scientific Advisory Committee is composed of international experts in different fields.
The SOSCLC -AECC project: small cell lung cancer. From biological networks to personalized therapy is an ‘AECC 70% Survival Challenge Grant’, aimed at projects that respond to an unresolved clinical need, hoping to increase the survival of a type of cancer with low survival and with a wide national geographical distribution, such as liver and, in this case, lung cancer.