Scientific Programmes

Biotechnology Programme

Histopathology Core Unit

Head of Unit:  vacancy
Overview

Pathology is devoted to the study of the structural, biochemical and functional changes in cells, tissues and organs that underlie disease. By using molecular, immunological and morphological techniques, pathology serves as the bridge between the basic sciences and clinical medicine.

The Histopathology Core Unit offers knowledge and expertise through a full range of services encompassing paraffin embedding and cutting, as well as the construction of tissue microarrays (TMAs). We also provide our users with histochemical stains upon request, research and diagnostic immunohistochemistry (IHC) testing, antibody validation, and in situ hybridisation (ISH) (ALU sequences for mouse xenograft characterisation). Furthermore, the Unit offers other services, such as laser-capture microdissection; slide digitalisation for brightfield, polarisation light and fluorescence; image analysis; and quantification. The Unit collaborates with researchers at any stage of their career in the histological characterisation of phenotypically relevant animal models of disease, thus providing them with the Pathology expertise required for the success of their research projects.