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Structural Biology Programme

Spectroscopy and Nuclear Magnetic Resonance Unit

Head of Unit:  Ramón Campos-Olivas
Overview

The Unit unifies the technical and scientific management of Nuclear Magnetic Resonance Spectroscopy (NMR) and of other biophysical instrumentation available through the Structural Biology and Biocomputing Programme. It provides CNIO researchers with instrumentation and technical support for a variety of spectroscopic and biophysical techniques. This includes the application of NMR to the in vitro characterisation of the structure and dynamics of biomolecules (proteins in particular) and their interactions with other biopolymers, as well as with small molecules that could represent initial hits in the drug discovery process or research compounds for biophysical and functional studies. Furthermore, we use NMR to characterise the metabolic profiles of biofluids, cell growth media and cell and tissue extracts from both animal models of cancer and human samples.