Alfonso Valencia is a biologist with formal training in population genetics and biophysics which he received from the Universidad Complutense de Madrid. He was awarded his PhD in 1988 at the Universidad Autónoma de Madrid.
He was a Visiting Scientist at the American Red Cross Laboratory in 1987 and from 1989-1994 was a Postdoctoral Fellow at the laboratory of C. Sander at the European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
In 1994 Alfonso Valencia set up the Protein Design Group at the Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC) in Madrid where he was appointed as Research Professor in 2005.
He is a Member of the European Molecular Biology Organisation (EMBO), Founder and former Vice President of the International Society for Computational Biology where he has been Chair of the Systems Biology and/or Text Mining Tracks of the main Computational Biology Annual Conference (ISMB) since 2003. He was honoured as ISCB-Fellow in 2010.
Alfonso Valencia serves on the Scientific Advisory Board of the European Molecular Biology Laboratory; the Swiss Institute for Bioinformatics, Biozentrum, Basel; the INTERPRO database; the Spanish Grant Evaluation Agency (ANEP); as well as the Steering Committee of the European Science Foundation Programme on Functional Genomics (2006-2011).
Alfonso Valencia is Co-Executive Editor of Bionformatics, serves on the Editorial Board of EMBO Journal and EMBO Reports, among others. He is the Director of the Spanish National Bioinformatics Institute (INB).